An efficient synthesis of phosphonate derivatives and stable phosphorus ylids by three-component reaction between phosphines or phosphites, benzil hydrazone and dialkyl acetylenedicarboxylates

An Efficient Synthesis of 4H-chromene Derivatives by a One-pot, Three-component Reaction

A facile and efficient one-pot, multicomponent synthesis of 4H-chromenes is reported, through the reaction of arylglyoxalmonohydrates with 1,3-diketones and malononitrile in eTEMPthanol in the presence of L-proline as a catalyst.

Diastereoselective Synthesis of Stable Phosphorus Yields by a Three-Component Reaction between Ph3P and Acetylenic Esters in the Presence of Hydrazine Derivatives

In this work, stable crystalline phosphorus yields are obtained in good yields from the 1:1:1 addition reactions between hydrazine derivatives and dialkyl acetylenedicarboxylates in the presence of triphenylphosphine at room temperature in dichloromethane. This synthetic method has merits of high yields, mild reaction conditions, and simple experimental and work-up conditions. The obtained yiel...

One-pot Three-component Synthesis of Phosphonate Derivatives

The stable phosphonate derivatives have easily synthesized by the reactions involving trialkyl(aryl) phosphites and dimethyl acetylenedicarboxylate in the presence of 4-nitrophenol and/or acid chlorides, dialkyl(aryl) phosphites and N-methylimidazole at 70 oC under solventfree conditions.

One-pot Four-component Reaction between Arylamines, Arylglyoxals, Cyclohexyl Isocyanide, and Acetylene Diesters: An Efficient Synthesis of 2H-iminopyran Derivatives

A facile synthesis of highly functionalized 2H-iminopyran derivatives by the multi-component reaction of cyclohexyl isocyanide, dialkyl acetylenedicarboxylates, arylglyoxals and arylamines is described. The zwitterionic intermediate produced by addition of cyclohexyl isocyanide to electron-deficient acetylene diesters was trapped by the electrophilic imine moiety of α-iminoketones, derived from...

diastereoselective synthesis of stable phosphorus yields by a three-component reaction between ph3p and acetylenic esters in the presence of hydrazine derivatives